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In this section, we present articles about the benefits of Lithothamnion and scientific studies about this organic compound. To send your articles, contact us by email tecnico@litholife.com.br and we will answer as soon as possible.

The use of Lithothamnion in food fortification

Calcium is added to all fortified milk substitutes (such as drinks, yoghurt alternatives and desserts) at a quantity of 120 mg per 100 g or per 100 mL. This quantity imitates the quantity of calcium found in milk. Products which are produced in accordance with the EU Directive for Organic Food always contain calcium additives in the form of Lithothamnion calcareum, a marine seaweed.

Other calcium-rich natural foods often contain absorption-inhibiting substances such as phytic acids, oxalic acids or various dietary fibers. As regards fortified foods, the alignment of milk substitutes such as soy drinks, fruit juices or yoghurt alternatives to the corresponding dairy products is a good measure, as the calcium content of these products thereby corresponds to that of the substituted goods. “Soy yoghurt” also contains fewer phytates than untreated soy; these are removed when the soy beans are soaked.

Thanks to a combination of calcium-rich natural foods, fortified vegan milk and dairy alternatives and calcium-rich mineral water, it is easy to guarantee supply of calciumin Germany nowadays for aged between 25 to 50.

Source: MARCZYKOWSKI, Felix. BREIDENASSEL, Chritina. Vegan diet: Reaching the reference values for nutrient intake of critical nutrients Assortment and necessity of fortified foods. Science & Research. March, 2016.

The nutrients impact on bones health

Nutrition is an important factor in bone maintenance and in osteoporosis prevention. This disease is characterized by decreased skeletal mass and increased susceptibility to fractures. The greatest determinant of this condition is the peak bone mass (PBM).

Hence, alterations over time indicate the importance of maintaining adequate nutrition during the development of this peak. In adult age, individuals who reached a high PBM will have a low risk of developing bone metabolic diseases when aging. The effects of nutrients over skeletal structures are wide and intense. Some of them have been consistently related with bone health, such as calcium, phosphorus and vitamin D. However, it has been suggested that other nutrients are essential for normal bone metabolism: proteins, lipids, potassium, vitamins K and A, and sodium chloride.

The influence of interactions between these nutritional factors, environment, lifestyle, and heredity will help understand the complex development of osteoporosis and subsequent fractures. In addition, energy deficits can lead to reduced bone mass, due to endocrine-metabolic disorders caused by food deprivation. This review aims at clarifying the impact of nutrients and of calories intake on the bones during different stages in life, describing possible interactions among nutrients and how these could affect bone and mineral homeostasis.

Keywords – Osteoporosis/prevention & control; Fractures, bone/prevention & control; Nutrients; Nutritional requirements; Micronutrients; Carbonated beverages

Source: GLAUCIA QUEIROZ MORAIS, MARIA GORETTI PESSOA DE ARAÚJO BURGOS. Rev Bras Ortop. 2007;42(7):189-94. Recebido em 25/10/06. Aprovado para publicação em 27/7/07.

Lithothamnion Farmacological activity

There are also studies showing the eficacy of Lithothamnium extracts in suppressing cancer cells growth: Proliferation and differentiation were assessed in a series of human colon carcinoma cell lines in response to a mineral-rich extract derived from the red marine algae, Lithothamniun calcareum. The extract contains 12% Ca2+, 1%Mg2+, and detectable amounts of 72 trace elements, but essentially no organic material. The red algae extract was as effective as inorganic Ca2+ alone in suppressing growth and inducing differentiation of colon carcinoma cells that are responsive to a physiological level of extracellular Ca2+ (1.4 mM). However,with cells that are resistant to Ca2+ alone, the extract was still able to reduce proliferation and stimulate differentiation.

Source: **ASLAM Muhammad Nadeem et. al. Growth-inhibitory effects of a mineralized extract from the red marine algae, Lithothamnion calcareum, on Ca2+-sensitive and Ca2+-resistant human colon carcinoma cells.
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